Multivariate analysis of 3D ToF-SIMS images: method validation and application to cultured neuronal networks.
نویسندگان
چکیده
Advanced data analysis tools are crucial for the application of ToF-SIMS analysis to biological samples. Here, we demonstrate that by using a training set approach principal components analysis (PCA) can be performed on large 3D ToF-SIMS images of neuronal cell cultures. The method readily provides access to sample component information and significantly improves the images' signal-to-noise ratio (SNR).
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ورودعنوان ژورنال:
- The Analyst
دوره 141 1 شماره
صفحات -
تاریخ انتشار 2016